Grid computing is the use of widely distributed computer resources to reach a common goal. A computing grid can be thought of as a distributed system with non-interactive workloads that involve many files. Grid computing is distinguished from conventional high-performance computing systems such as cluster computing in that grid computers have each node set to perform a different task/application. Grid computers also tend to be more heterogeneous and geographically dispersed (thus not physically coupled) than cluster computers. Although a single grid can be dedicated to a particular application, commonly a grid is used for a variety of purposes. Grids are often constructed with general-purpose grid middleware software libraries. Grid sizes can be quite large.

Grids are a form of distributed computing composed of many networked loosely coupled computers acting together to perform large tasks. For certain applications, distributed or grid computing can be seen as a special type of parallel computing that relies on complete computers (with onboard CPUs, storage, power supplies, network interfaces, etc.) connected to a computer network (private or public) by a conventional network interface, such as Ethernet. This is in contrast to the traditional notion of a supercomputer, which has many processors connected by a local high-speed computer bus. This technology has been applied to computationally intensive scientific, mathematical, and academic problems through volunteer computing, and it is used in commercial enterprises for such diverse applications as drug discovery, economic forecasting, seismic analysis, and back office data processing in support for e-commerce and Web services.

Grid computing combines computers from multiple administrative domains to reach a common goal, to solve a single task, and may then disappear just as quickly. The size of a grid may vary from small—confined to a network of computer workstations within a corporation, for example—to large, public collaborations across many companies and networks. "The notion of a confined grid may also be known as an intra-nodes cooperation whereas the notion of a larger, wider grid may thus refer to an inter-nodes cooperation".

Coordinating applications on Grids can be a complex task, especially when coordinating the flow of information across distributed computing resources. Grid workflow systems have been developed as a specialized form of a workflow management system designed specifically to compose and execute a series of computational or data manipulation steps, or a workflow, in the grid context.